Tuesday, January 27, 2015
Sunday, October 19, 2014
OMICS GROUP CONFERENCE - MY TALK
Raja Chakraverty |
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| Raja Chakraverty Bengal College of Pharmaceutical Sciences and Research India | |
TITLE: Current evidence on the effect of DPP-4 inhibitor drugs on mortality in type 2 diabetic (T2D) patients: A meta-analysis | |
| Abstract | |
This meta-analysis throws light on the current understanding from concluded randomized controlled trials (RCTs) before 2014 on the extent of impact of dipeptidyl peptidase-4 inhibitor(DPP-4 I)drugs on overall mortality in patients of type 2 diabetes mellitus.TheDPP-4 inhibitor class representsa relatively newer class of oral antidiabetic agents that facilitate improved glycemic control and improvement in glycosylated haemoglobin levels (HbA1c) in patients with type 2 diabetes mellitus. The present meta-analysis is aimed at all randomized controlled trials involving that were published before February 2014 was carried out. Published articles in bibliographic and abstracting electronic databases such as Pubmed central, Cochrane reviews andother medical journals served as the data sources for the present study. The article selection criteria included all randomized placebo-controlled trials of at least one year duration and those which measured at least one of the following clinical endpoints: risk ratio, coronary artery disease mortality, cardio-vascular mortality or all-cause mortality. Information on sample size, follow up period, drug used, and clinical outcomes was abstracted independently by the authors. The present meta-analysis compiled pooled data from 18 randomised controlled trials (RCTs) fulfilling the inclusion criteria of the study (18 trials, 5903 patients) showed a significant relative risk reduction of coronary artery disease mortality, cardiovascular disease mortality and on all-cause mortality without any significant heterogeneity and inconsistency between the trials. From these findings was inferred from the findings from this meta-analyses that the dipeptidyl peptidase-4 inhibitors are indeed effective medicines that confer benefit to patients, in terms of affording optimal glycemic control in T2 DM patients and disease control.
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| Biography | |
Raja Chakraverty has pursued his B Pharm from GNIPST, Kolkata under West Bengal University of Technology and his M Pharm in Pharmacology from Gupta College of Technological Sciences, Asansol. He has also pursued his masters̢۪ project work from the Department of Clinical & Experimental Pharmacology at Calcutta School of Tropical Medicine, Kolkata. He has to his credit published ten (10) original research articles in various indexed national and international journals in Pharmaceutical Sciences. His research interest lies in the comprehensive preclinical studies of polyherbal formulations, particularly in the pharmacological screening of anti diabetic drugs in animal models, data mining and meta-analysis, clinical research of pharmaceuticals and biologicals, in pharmacovigilanceof herbal medicines and toxicological studies.
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Monday, August 18, 2014
'THE WORLD IS GOING TO HELL'
2. UKRAINE-RUSSIA STANDOFF
3. WEST BANK BLOODSHED
4. NOT BETTER IN IRAQ
5. LIBYA NOT SAFE
6. INDIA N THE CLUTCHES OF MALDEVELOPMENT
Thursday, May 22, 2014
A DAY @ RIVERSIDE
http://kolkatakev.files.wordpress.com/2012/06/20sunset-riverside.jpg
Sunday, July 14, 2013
Tuesday, March 5, 2013
ANIMAL INSTINCTS
Saturday, November 10, 2012
Tuesday, June 26, 2012
The Indian Presidential elections of 2012- Much Ado about Nothing ?
Our Government certainly needs to get its priorities right !
Tuesday, April 3, 2012
Saturday, December 31, 2011
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES & RESEARCH
Friday, December 30, 2011
December 31st, 2011 a year in retrospect
Friday, December 2, 2011
Saturday, October 29, 2011
memories of months
January-sound sleep, dreamy eyes, hunt for calendars, silent air, catching up on cricket down under usually in the early wee hours of the morning…
February- Shortest month in the calendar, Feeling Lovesick, romantic movie season, saraswati ma puja at my home, cricket in west indies, runny nose,fever, chill, bodyache,under the weather everytime..
March- Holi, memories of all those years spent in exams, switching on the fun for the very first time the year ( nostalgia ) and film awards, blooming of flowers...
April- Bengal celebrates Nabobarsho with much pomp and gaiety, things are heating up weatherwise around this time…
May- Evenings are half as pleasant as the mornings harsh, body scorches and liquid intake, air conditioners, rising electricity bills, frequent power cuts, ill temper..
June- Intense heat, want some respite, AC in full steam, Kulfi ,praying for thunderstorms and rains and repenting having asked for it later on; usually holiday month since school, has remained so…
July- Rains and colling of the airs, music, aura of romanticism..
August- Patriotism fills the air....concerts..hope.
September- Countdown to Durgotsav and body wanting a break …holidays ??
October- Usually the most festive month having usually many holidays including Glittering lights of Diwali ..Free to do as I choose plus good food generally helps...
November- Solemn month, pollution, winter just setting in..
December-Under the mattress,pollution and dust, cakes and heavy breakfast, Fan no longer needed, playing cricket, Christmas, 31st night shows on TV and making new year resolutions hoping / praying a better year in next one..




